PBX1 Attenuates Hair Follicle-Derived Mesenchymal Stem Cell Senescence and Apoptosis by Alleviating Reactive Oxygen Species-Mediated DNA Damage Instead of Enhancing DNA Damage Repair

PBX1 Attenuates Hair Follicle-Derived Mesenchymal Stem Cell Senescence and Apoptosis by Alleviating Reactive Oxygen Species-Mediated DNA Damage Instead of Enhancing DNA Damage Repair

Tissues and organs undergo structural deterioration and functional decline during aging. DNA damage is considered a major cause of stem cell senescence. Although stem cells develop sophisticated DNA repair systems, when the intrinsic and extrinsic insults exceed the DNA repair capacity, cellular sen...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Yuan Wang, Yutong Sui, Aobo Lian, Xing Han, Feilin Liu, Kuiyang Zuo, Mingsheng Liu, Wei Sun, Ziyu Wang, Zinan Liu, Fei Zou, Rifeng Lu, Minghua Jin, Haiying Du, Kan Xu, Xiaomei Liu, Jinyu Liu
Formato: article
Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
Materias:
PBX1
hair follicle (HF)
mesenchymal stem cells
senescence
apoptosis
DNA damage and repair
Biology (General)
QH301-705.5
Acceso en línea:https://doaj.org/article/873db1c2202e458287cbaefe8d5dce57
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Internet

https://doaj.org/article/873db1c2202e458287cbaefe8d5dce57

Ejemplares similares