To Discover the Efficient and Novel Drug Targets in Human Cancers Using CRISPR/Cas Screening and Databases

CRISPR/Cas has emerged as an excelle nt gene-editing technology and is used worldwide for research. The CRISPR library is an ideal tool for identifying essential genes and synthetic lethality targeted for cancer therapies in human cancers. Synthetic lethality is defined as multiple genetic abnormali...

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Bibliographic Details
Main Authors: Iichiroh Onishi, Kouhei Yamamoto, Yuko Kinowaki, Masanobu Kitagawa, Morito Kurata
Format: article
Language:EN
Published: MDPI AG 2021
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Online Access:https://doaj.org/article/875a5219042e49beb189ce78fc532fab
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