How single mutations affect viral escape from broad and narrow antibodies to H1 influenza hemagglutinin

Influenza A virus can escape antibodies, but it is unclear how the ease of escape depends on the epitope targeted by an antibody. Here, the authors show that neutralization breadth is an imperfect indicator of the ease of viral escape by single mutations, and that antibodies targeting the stalk of h...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Michael B. Doud, Juhye M. Lee, Jesse D. Bloom
Format: article
Langue:EN
Publié: Nature Portfolio 2018
Sujets:
Q
Accès en ligne:https://doaj.org/article/876257bdebd1481d98820158c8928e1b
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!