How single mutations affect viral escape from broad and narrow antibodies to H1 influenza hemagglutinin
Influenza A virus can escape antibodies, but it is unclear how the ease of escape depends on the epitope targeted by an antibody. Here, the authors show that neutralization breadth is an imperfect indicator of the ease of viral escape by single mutations, and that antibodies targeting the stalk of h...
Guardado en:
Autores principales: | Michael B. Doud, Juhye M. Lee, Jesse D. Bloom |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
|
Materias: | |
Acceso en línea: | https://doaj.org/article/876257bdebd1481d98820158c8928e1b |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
In vitro evolution of an influenza broadly neutralizing antibody is modulated by hemagglutinin receptor specificity
por: Nicholas C. Wu, et al.
Publicado: (2017) -
Vaccination with a Recombinant H7 Hemagglutinin-Based Influenza Virus Vaccine Induces Broadly Reactive Antibodies in Humans
por: Daniel Stadlbauer, et al.
Publicado: (2017) -
Influenza Virus Infection Induces a Narrow Antibody Response in Children but a Broad Recall Response in Adults
por: Philip Meade, et al.
Publicado: (2020) -
Epigraph hemagglutinin vaccine induces broad cross-reactive immunity against swine H3 influenza virus
por: Brianna L. Bullard, et al.
Publicado: (2021) -
Cross-lineage protection by human antibodies binding the influenza B hemagglutinin
por: Yi Liu, et al.
Publicado: (2019)