PEP-19 modulates calcium binding to calmodulin by electrostatic steering

The protein PEP-19 increases the rates of calcium binding to calmodulin. Here, the authors report the structure of PEP-19 bound to the C-terminal domain of calmodulin, and are able to propose a mechanism for the observed increased calcium association rate.

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Detalles Bibliográficos
Autores principales: Xu Wang, John A. Putkey
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Q
Acceso en línea:https://doaj.org/article/87656c6f7cf54997bf12ecd08c72d76c
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