BX-795 inhibits neuroblastoma growth and enhances sensitivity towards chemotherapy

High-risk neuroblastoma (NB) represents a major clinical challenge in pediatric oncology due to relapse of metastatic, drug-resistant disease, and treatment-related toxicities. An analysis of 1235 primary NB patient dataset revealed significant increase in AKT1 and AKT2 gene expression with cancer s...

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Auteurs principaux: Rameswari Chilamakuri, Danielle C. Rouse, Yang Yu, Abbas S. Kabir, Aaron Muth, Jianhua Yang, Jeffery M. Lipton, Saurabh Agarwal
Format: article
Langue:EN
Publié: Elsevier 2022
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Accès en ligne:https://doaj.org/article/876fff3a8ac947789e0b637412ec2d83
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