Molecular characterisation of endogenous Vangl2/Vangl1 heteromeric protein complexes.

Molecular characterisation of endogenous Vangl2/Vangl1 heteromeric protein complexes.

<h4>Background</h4>Mutations in the Planar Cell Polarity (PCP) core gene Vangl2 cause the most severe neural tube defects (NTD) in mice and humans. Genetic studies show that the Vangl2 gene genetically interacts with a close homologue Vangl1. How precisely Vangl2 and Vangl1 proteins inte...

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Autores principales: Edwige Belotti, Tania M Puvirajesinghe, Stéphane Audebert, Emilie Baudelet, Luc Camoin, Michel Pierres, Lea Lasvaux, Géraldine Ferracci, Mireille Montcouquiol, Jean-Paul Borg
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Medicine
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Science
Q
Acceso en línea:https://doaj.org/article/87709adb080a4559b31b0d6be284f9a3
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https://doaj.org/article/87709adb080a4559b31b0d6be284f9a3

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