Mmm-derived lipid-associated membrane proteins activate IL-1β production through the NF-κB pathway via TLR2, MyD88, and IRAK4

Abstract Mycoplasma mycoides subsp.mycoides (Mmm) is a pathogen that causes pneumonia, otitis media, and arthritis in young calves. Its pathogenesis is attributed in part to excessive immune responses. Mmm-derived lipid-associated membrane proteins (LAMPs) are potent inducers of the host innate immu...

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Autores principales: Yang Wang, Qi Wang, Yuan Li, Ying Chen, Jiari Shao, Nwankpa Nick, Chunyan Li, Jiuqing Xin
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/8782e605d3e644bb8ecb66767f9336a0
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