B cells inhibit bone formation in rheumatoid arthritis by suppressing osteoblast differentiation
B cells contribute to rheumatoid arthritis pathogenesis and bone erosion, but the underlying mechanisms are still unclear. Here the authors show, using mouse models and patient tissues, that B cells directly inhibit osteoblast differentiation by producing CCL3 and TNF, thereby providing a potentiall...
Saved in:
| Main Authors: | , , , , , , , , , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2018
|
| Subjects: | |
| Online Access: | https://doaj.org/article/879bcc165f4342d5914461b4c9efd208 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|