IDKK1 inhibits canonical Wnt signaling in human papillomavirus-positive penile cancer cells

IDKK1 inhibits canonical Wnt signaling in human papillomavirus-positive penile cancer cells

Penile squamous cell cancer (PSCC) is the most frequent penile malignant disease. Infections with human papillomaviruses (HPV) are a major etiologic driver of PSCC. However, the molecular details of the underlying carcinogenesis are understudied because of rare clinical specimens and missing cell li...

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Main Authors: Isabelle Ariane Bley, Anabel Zwick, Muriel Charlotte Hans, Katrin Thieser, Viktoria Wagner, Nicole Ludwig, Oybek Khalmurzaev, Vsevolod Borisovich Matveev, Philine Loertzer, Alexey Pryalukhin, Arndt Hartmann, Carol-Immanuel Geppert, Hagen Loertzer, Heiko Wunderlich, Carsten Maik Naumann, Holger Kalthoff, Kerstin Junker, Sigrun Smola, Stefan Lohse
Format: article
Language:EN
Published: Elsevier 2022
Subjects:
β-catenin
Dickkopf1
HPV
Penile cancer
Wnt pathway
Stemness
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Online Access:https://doaj.org/article/87a28aa8aacd4a919e9d6017b6163a14
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https://doaj.org/article/87a28aa8aacd4a919e9d6017b6163a14

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