Expression of truncated Kir6.2 promotes insertion of functionally inverted ATP-sensitive K+ channels

Abstract ATP-sensitive K+ (KATP) channels couple cellular metabolism to electrical activity in many cell types. Wild-type KATP channels are comprised of four pore forming (Kir6.x) and four regulatory (sulfonylurea receptor, SURx) subunits that each contain RKR endoplasmic reticulum retention sequenc...

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Auteurs principaux: Benjamin A. Heitz, Robert Bränström, Wei Yang, Yiding Huang, Tilo Moede, Ingo B. Leibiger, Barbara Leibiger, Liu Qi Chen, Jia Yu, Shao-Nian Yang, Olof Larsson, S. Scott Saavedra, Per-Olof Berggren, Craig A. Aspinwall
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Q
Accès en ligne:https://doaj.org/article/87b22a90ce764dbc9e3214f3647c135f
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