A novel system-level approach using RNA-sequencing data identifies miR-30-5p and miR-142a-5p as key regulators of apoptosis in myocardial infarction

A novel system-level approach using RNA-sequencing data identifies miR-30-5p and miR-142a-5p as key regulators of apoptosis in myocardial infarction

Abstract This study identified microRNAs involved in myocardial infarction (MI) through a novel system-level approach using RNA sequencing data in an MI mouse model. This approach involved the extraction of DEGs and DEmiRs from RNA-seq data in sham and MI samples and the subsequent selection of two...

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Autores principales: Jin Ock Kim, Jei Hyoung Park, Taeyong Kim, Seong Eui Hong, Ji Young Lee, Kyoung Jin Nho, Chunghee Cho, Yong Sook Kim, Wan Seok Kang, Youngkeun Ahn, Do Han Kim
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
System-level Approach
Neonatal Rat Ventricular Myocytes (NRVMs)
Differentially Expressed Genes (DEGs)
Gene Set Enrichment Analysis (GSEA)
Fragments Per Kilobase Of Exon Per Million Fragments (FPKM)
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/87f602c9a40c4a7f8e59fe82557b8e0d
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https://doaj.org/article/87f602c9a40c4a7f8e59fe82557b8e0d

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