Theoretical principles of transcription factor traffic on folded chromatin

How transcription factors find their targets in vivo is still poorly understood. Here the authors use molecular dynamics simulations to investigate how transcription factors diffuse on chromatin, providing a theoretical framework for understanding the key role of genome conformation in this process.

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Detalles Bibliográficos
Autores principales: Ruggero Cortini, Guillaume J. Filion
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
Q
Acceso en línea:https://doaj.org/article/8818853b5c76420db353655d10fd7053
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