Radiogenomic signatures reveal multiscale intratumour heterogeneity associated with biological functions and survival in breast cancer

Tumours are made up of heterogeneous subclones. Here, the authors show using breast cancer imaging and gene expression datasets that these subclones can be inferred by the deconvolution of gene expression data, mapped to MRI derived radiogenomic signatures and used to estimate prognosis.

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Detalles Bibliográficos
Autores principales: Ming Fan, Pingping Xia, Robert Clarke, Yue Wang, Lihua Li
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/881d41ad02f34b639dffa6a53f36c8c9
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