Rolling circle transcription of ribozymes from promoterless single-stranded DNA nanocircles in mammalian cells [Ribozimlerin, promotorsuz tek-iplikli DNA çemberlerinin rolling circle transkripsiyonu ile memeli hücrelerinde üretimi]

Self-processing hairpin ribozymes have been synthesized from promoterless singlestranded DNA circles (73 nt) within mammalian cells. Following lipid-mediated transient transfection, DNA circles were efficiently internalized by mouse L cells (OST7–1) that stably express T7 RNA polymerase confining...

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Autor principal: Attila A. Seyhan
Formato: article
Lenguaje:EN
Publicado: De Gruyter 2006
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Acceso en línea:https://doaj.org/article/887677e0d0894a6b980c8dd7497b3fb1
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