Analysis of Mutations and Dysregulated Pathways Unravels Carcinogenic Effect and Clinical Actionability of Mutational Processes

Somatic mutations accumulate over time in cancer cells as a consequence of mutational processes. However, the role of mutational processes in carcinogenesis remains poorly understood. Here, we infer the causal relationship between mutational processes and somatic mutations in 5,828 samples spanning...

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Autores principales: Zedong Jiang, Gaoming Liao, Yiran Yang, Yujia Lan, Liwen Xu, Min Yan, Yao Zhou, Jiali Zhu, Wei Liu, Jing Bai, Yun Xiao, Xia Li
Formato: article
Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
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Acceso en línea:https://doaj.org/article/887b25e876c84bf39e9988d4dc05e387
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