Flexible experimental designs for valid single-cell RNA-sequencing experiments allowing batch effects correction
It is not clear which designs, other than completely randomized ones, are valid for scRNA-seq experiments so that batch effects can be adjusted. Here the authors show that under flexible reference panel and chain-type designs, biological variability can also be separated from batch effects, at least...
Guardado en:
Autores principales: | Fangda Song, Ga Ming Angus Chan, Yingying Wei |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
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Materias: | |
Acceso en línea: | https://doaj.org/article/889067254b4d4524ba0685f276a62942 |
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