Combination of epigenetic regulation with gene therapy-mediated immune checkpoint blockade induces anti-tumour effects and immune response in vivo

While immunotherapy is a promising cancer treatment option, durable benefits are often rare due to immune escape. Here, the authors combine epigenetic regulation with gene therapy-mediated immune checkpoint blockade and show efficient anti-tumour effects and immune response in vivo.

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Auteurs principaux: Huapan Fang, Zhaopei Guo, Jie Chen, Lin Lin, Yingying Hu, Yanhui Li, Huayu Tian, Xuesi Chen
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/88a68866c470414a9fb6c60275bc712b
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