CNOT6 regulates a novel pattern of mRNA deadenylation during oocyte meiotic maturation

Abstract In many cell types, the length of the poly(A) tail of an mRNA is closely linked to its fate - a long tail is associated with active translation, a short tail with silencing and degradation. During mammalian oocyte development, two contrasting patterns of polyadenylation have been identified...

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Autores principales: Karl-Frédéric Vieux, Hugh J. Clarke
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/88be864bde564d92b1c953d226a7f749
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