The formation of the Bicoid morphogen gradient requires protein movement from anteriorly localized mRNA.

The Bicoid morphogen gradient directs the patterning of cell fates along the anterior-posterior axis of the syncytial Drosophila embryo and serves as a paradigm of morphogen-mediated patterning. The simplest models of gradient formation rely on constant protein synthesis and diffusion from anteriorl...

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Autores principales: Shawn C Little, Gašper Tkačik, Thomas B Kneeland, Eric F Wieschaus, Thomas Gregor
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
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Acceso en línea:https://doaj.org/article/88d21b9df7364cb2b41c0b3f1e3fe70b
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