A Genome-Wide Knockout Screen in Human Macrophages Identified Host Factors Modulating <italic toggle="yes">Salmonella</italic> Infection
ABSTRACT A genome-scale CRISPR knockout library screen of THP-1 human macrophages was performed to identify loss-of-function mutations conferring resistance to Salmonella uptake. The screen identified 183 candidate genes, from which 14 representative genes involved in actin dynamics (ACTR3, ARPC4, C...
Saved in:
| Main Authors: | , , , , , , , , , , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
American Society for Microbiology
2019
|
| Subjects: | |
| Online Access: | https://doaj.org/article/88e1f65dbd364ffc8b38e80865afebb5 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|