Development of novel 123I-labeled pyridyl benzofuran derivatives for SPECT imaging of β-amyloid plaques in Alzheimer's disease.

Imaging of β-amyloid (Aβ) plaques in the brain may facilitate the diagnosis of cerebral β-amyloidosis, risk prediction of Alzheimer's disease (AD), and effectiveness of anti-amyloid therapies. The purpose of this study was to evaluate novel (123)I-labeled pyridyl benzofuran derivatives as SPECT...

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Autores principales: Masahiro Ono, Yan Cheng, Hiroyuki Kimura, Hiroyuki Watanabe, Kenji Matsumura, Masashi Yoshimura, Shimpei Iikuni, Yoko Okamoto, Masafumi Ihara, Ryosuke Takahashi, Hideo Saji
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/88f0203eb2224c83b97fd46640d134b1
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