Development of novel 123I-labeled pyridyl benzofuran derivatives for SPECT imaging of β-amyloid plaques in Alzheimer's disease.
Imaging of β-amyloid (Aβ) plaques in the brain may facilitate the diagnosis of cerebral β-amyloidosis, risk prediction of Alzheimer's disease (AD), and effectiveness of anti-amyloid therapies. The purpose of this study was to evaluate novel (123)I-labeled pyridyl benzofuran derivatives as SPECT...
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Main Authors: | Masahiro Ono, Yan Cheng, Hiroyuki Kimura, Hiroyuki Watanabe, Kenji Matsumura, Masashi Yoshimura, Shimpei Iikuni, Yoko Okamoto, Masafumi Ihara, Ryosuke Takahashi, Hideo Saji |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2013
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Online Access: | https://doaj.org/article/88f0203eb2224c83b97fd46640d134b1 |
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