Dearomative 1,4-difunctionalization of naphthalenes via palladium-catalyzed tandem Heck/Suzuki coupling reaction

Naphthalene is a challenging arene towards transition-metal-catalyzed dearomative difunctionalization. Here, the authors show that naphthalene may act as a masked conjugated diene in palladium-catalyzed dearomative 1,4-diarylation or 1,4-vinylarylation via a tandem Heck/Suzuki sequence.

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Auteurs principaux: Bo Zhou, Hongliang Wang, Zhong-Yan Cao, Jia-Wen Zhu, Ren-Xiao Liang, Xin Hong, Yi-Xia Jia
Format: article
Langue:EN
Publié: Nature Portfolio 2020
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Accès en ligne:https://doaj.org/article/89129853682a4f80a7f326b2d5c8704f
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