Lung eosinophils elicited during allergic and acute aspergillosis express RORγt and IL-23R but do not require IL-23 for IL-17 production.

Exposure to the mold, Aspergillus, is ubiquitous and generally has no adverse consequences in immunocompetent persons. However, invasive and allergic aspergillosis can develop in immunocompromised and atopic individuals, respectively. Previously, we demonstrated that mouse lung eosinophils produce I...

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Autores principales: Bhawna Yadav, Charles A Specht, Chrono K Lee, Maria Pokrovskii, Jun R Huh, Dan R Littman, Stuart M Levitz
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
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Acceso en línea:https://doaj.org/article/893508723fee4f4d95a8d4fb9de9b234
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