HLA-G gene editing in tumor cell lines as a novel alternative in cancer immunotherapy

Abstract Cancer immunotherapies based mainly on the blockade of immune-checkpoint (IC) molecules by anti-IC antibodies offer new alternatives for treatment in oncological diseases. However, a considerable proportion of patients remain unresponsive to them. Hence, the development of novel clinical im...

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Autores principales: María Belén Palma, Diana Tronik-Le Roux, Guadalupe Amín, Sheila Castañeda, Alan M. Möbbs, María Agustina Scarafia, Alejandro La Greca, Marina Daouya, Isabelle Poras, Ana María Inda, Lucía N. Moro, Edgardo D. Carosella, Marcela N. García, Santiago G. Miriuka
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/894a26ff5d8c49e7b84811e2e58054c0
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