Limonin Inhibits IL-1β-Induced Inflammation and Catabolism in Chondrocytes and Ameliorates Osteoarthritis by Activating Nrf2

Osteoarthritis (OA), a degenerative disorder, is considered to be one of the most common forms of arthritis. Limonin (Lim) is extracted from lemons and other citrus fruits. Limonin has been reported to have anti-inflammatory effects, while inflammation is a major cause of OA; thus, we propose that l...

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Main Authors: Jie Jin, Xinhuang Lv, Ben Wang, Chenghao Ren, Jingtao Jiang, Hongyu Chen, Ximiao Chen, Mingbao Gu, Zongyou Pan, Naifeng Tian, Aimin Wu, Liaojun Sun, Weiyang Gao, Xiangyang Wang, Xiaolei Zhang, Yaosen Wu, Yifei Zhou
Format: article
Language:EN
Published: Hindawi Limited 2021
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Online Access:https://doaj.org/article/8956271a540e48a58adacfd5ea6f9411
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