MglA functions as a three-state GTPase to control movement reversals of Myxococcus xanthus

In Myxococcus xanthus, directed movement is controlled by pole-to-pole oscillations of the small GTPase MglA and its GAP MglB. Here authors report the complete MglA/MglB structural cycle and uncover that MglA is a three-state GTPase that adopts an atypical GTP-bound state that is refractory to inact...

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Autores principales: Christian Galicia, Sébastien Lhospice, Paloma Fernández Varela, Stefano Trapani, Wenhua Zhang, Jorge Navaza, Julien Herrou, Tâm Mignot, Jacqueline Cherfils
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/898fe1ad02c946998bee71bbdb3219d7
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