Characterization and structural basis of a lethal mouse-adapted SARS-CoV-2
In this study, Qin et al. present a murine-adapted SARS-CoV-2 strain, MASCp36, as a model for studying the pathogenicity, evolution and adaptation of the virus to human and animal hosts.
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Nature Portfolio
2021
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oai:doaj.org-article:899a2a1eed80467f96aa38de7207946b2021-12-02T17:37:30ZCharacterization and structural basis of a lethal mouse-adapted SARS-CoV-210.1038/s41467-021-25903-x2041-1723https://doaj.org/article/899a2a1eed80467f96aa38de7207946b2021-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25903-xhttps://doaj.org/toc/2041-1723In this study, Qin et al. present a murine-adapted SARS-CoV-2 strain, MASCp36, as a model for studying the pathogenicity, evolution and adaptation of the virus to human and animal hosts.Shihui SunHongjing GuLei CaoQi ChenQing YeGuan YangRui-Ting LiHang FanYong-Qiang DengXiaopeng SongYini QiMin LiJun LanRui FengYan GuoNa ZhuSi QinLei WangYi-Fei ZhangChao ZhouLingna ZhaoYuehong ChenMeng ShenYujun CuiXiao YangXinquan WangWenjie TanHui WangXiangxi WangCheng-Feng QinNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Shihui Sun Hongjing Gu Lei Cao Qi Chen Qing Ye Guan Yang Rui-Ting Li Hang Fan Yong-Qiang Deng Xiaopeng Song Yini Qi Min Li Jun Lan Rui Feng Yan Guo Na Zhu Si Qin Lei Wang Yi-Fei Zhang Chao Zhou Lingna Zhao Yuehong Chen Meng Shen Yujun Cui Xiao Yang Xinquan Wang Wenjie Tan Hui Wang Xiangxi Wang Cheng-Feng Qin Characterization and structural basis of a lethal mouse-adapted SARS-CoV-2 |
| description |
In this study, Qin et al. present a murine-adapted SARS-CoV-2 strain, MASCp36, as a model for studying the pathogenicity, evolution and adaptation of the virus to human and animal hosts. |
| format |
article |
| author |
Shihui Sun Hongjing Gu Lei Cao Qi Chen Qing Ye Guan Yang Rui-Ting Li Hang Fan Yong-Qiang Deng Xiaopeng Song Yini Qi Min Li Jun Lan Rui Feng Yan Guo Na Zhu Si Qin Lei Wang Yi-Fei Zhang Chao Zhou Lingna Zhao Yuehong Chen Meng Shen Yujun Cui Xiao Yang Xinquan Wang Wenjie Tan Hui Wang Xiangxi Wang Cheng-Feng Qin |
| author_facet |
Shihui Sun Hongjing Gu Lei Cao Qi Chen Qing Ye Guan Yang Rui-Ting Li Hang Fan Yong-Qiang Deng Xiaopeng Song Yini Qi Min Li Jun Lan Rui Feng Yan Guo Na Zhu Si Qin Lei Wang Yi-Fei Zhang Chao Zhou Lingna Zhao Yuehong Chen Meng Shen Yujun Cui Xiao Yang Xinquan Wang Wenjie Tan Hui Wang Xiangxi Wang Cheng-Feng Qin |
| author_sort |
Shihui Sun |
| title |
Characterization and structural basis of a lethal mouse-adapted SARS-CoV-2 |
| title_short |
Characterization and structural basis of a lethal mouse-adapted SARS-CoV-2 |
| title_full |
Characterization and structural basis of a lethal mouse-adapted SARS-CoV-2 |
| title_fullStr |
Characterization and structural basis of a lethal mouse-adapted SARS-CoV-2 |
| title_full_unstemmed |
Characterization and structural basis of a lethal mouse-adapted SARS-CoV-2 |
| title_sort |
characterization and structural basis of a lethal mouse-adapted sars-cov-2 |
| publisher |
Nature Portfolio |
| publishDate |
2021 |
| url |
https://doaj.org/article/899a2a1eed80467f96aa38de7207946b |
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