Inhibition of Nox2 oxidase activity ameliorates influenza A virus-induced lung inflammation.

Influenza A virus pandemics and emerging anti-viral resistance highlight the urgent need for novel generic pharmacological strategies that reduce both viral replication and lung inflammation. We investigated whether the primary enzymatic source of inflammatory cell ROS (reactive oxygen species), Nox...

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Autores principales: Ross Vlahos, John Stambas, Steven Bozinovski, Brad R S Broughton, Grant R Drummond, Stavros Selemidis
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
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Acceso en línea:https://doaj.org/article/89a65053227b431bbd150918f57388f5
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