Cryo-EM structure of ABCG5/G8 in complex with modulating antibodies
Zhang et al. present the cryo-EM structure of ATP-binding cassette transporters ABCG5/G8 in complex with the Fab fragments from two monoclonal antibodies at 3.3 Å resolution. This study provides structural insights into the transport cycle and potential epitopes for therapeutic interventions that co...
Guardado en:
| Autores principales: | , , , , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2021
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/89adae28264f40d7b90ec8bef59c63f3 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|