BEST Endovascular Versus Best Surgical Therapy in Patients with Critical Limb Ischemia (BEST-CLI) Trial

The Best Endovascular versus Best Surgical Therapy in Patients with Critical Limb Ischemia trial (BEST-CLI) is an international, prospective, multicentre, multidisciplinary and pragmatic, open-label, superiority-based, comparative-effectiveness randomised controlled trial designed to address the kno...

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Main Authors: Raghu Motaganahalli, Matthew Menard, Matt Koopman, Alik Farber
Format: article
Language:EN
Published: Radcliffe Medical Media 2020
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Online Access:https://doaj.org/article/89debc152d0d4e1eb45cd94e7bd8247d
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spelling oai:doaj.org-article:89debc152d0d4e1eb45cd94e7bd8247d2021-12-04T16:02:48ZBEST Endovascular Versus Best Surgical Therapy in Patients with Critical Limb Ischemia (BEST-CLI) Trial10.15420/ver.2019.122516-33022516-3299https://doaj.org/article/89debc152d0d4e1eb45cd94e7bd8247d2020-05-01T00:00:00Zhttps://www.verjournal.com/articleindex/ver.2019.12https://doaj.org/toc/2516-3299https://doaj.org/toc/2516-3302The Best Endovascular versus Best Surgical Therapy in Patients with Critical Limb Ischemia trial (BEST-CLI) is an international, prospective, multicentre, multidisciplinary and pragmatic, open-label, superiority-based, comparative-effectiveness randomised controlled trial designed to address the knowledge gap in choosing the appropriate therapy for the treatment of critical limb ischaemia (CLI). This study compares the effectiveness of the best available surgical treatment with the best available endovascular treatment in adults with CLI who are eligible for both treatment options. The study has completed its enrolment phase and patients included in the study are currently being followed up to 50 months. Results of the study promise to provide us with answers to several questions regarding treatment options for patients with CLI, more recently referred to as chronic limb-threatening ischaemia.Raghu MotaganahalliMatthew MenardMatt KoopmanAlik FarberRadcliffe Medical MediaarticleDiseases of the circulatory (Cardiovascular) systemRC666-701ENVascular and Endovascular Review , Vol 3, Iss , Pp - (2020)
institution DOAJ
collection DOAJ
language EN
topic Diseases of the circulatory (Cardiovascular) system
RC666-701
spellingShingle Diseases of the circulatory (Cardiovascular) system
RC666-701
Raghu Motaganahalli
Matthew Menard
Matt Koopman
Alik Farber
BEST Endovascular Versus Best Surgical Therapy in Patients with Critical Limb Ischemia (BEST-CLI) Trial
description The Best Endovascular versus Best Surgical Therapy in Patients with Critical Limb Ischemia trial (BEST-CLI) is an international, prospective, multicentre, multidisciplinary and pragmatic, open-label, superiority-based, comparative-effectiveness randomised controlled trial designed to address the knowledge gap in choosing the appropriate therapy for the treatment of critical limb ischaemia (CLI). This study compares the effectiveness of the best available surgical treatment with the best available endovascular treatment in adults with CLI who are eligible for both treatment options. The study has completed its enrolment phase and patients included in the study are currently being followed up to 50 months. Results of the study promise to provide us with answers to several questions regarding treatment options for patients with CLI, more recently referred to as chronic limb-threatening ischaemia.
format article
author Raghu Motaganahalli
Matthew Menard
Matt Koopman
Alik Farber
author_facet Raghu Motaganahalli
Matthew Menard
Matt Koopman
Alik Farber
author_sort Raghu Motaganahalli
title BEST Endovascular Versus Best Surgical Therapy in Patients with Critical Limb Ischemia (BEST-CLI) Trial
title_short BEST Endovascular Versus Best Surgical Therapy in Patients with Critical Limb Ischemia (BEST-CLI) Trial
title_full BEST Endovascular Versus Best Surgical Therapy in Patients with Critical Limb Ischemia (BEST-CLI) Trial
title_fullStr BEST Endovascular Versus Best Surgical Therapy in Patients with Critical Limb Ischemia (BEST-CLI) Trial
title_full_unstemmed BEST Endovascular Versus Best Surgical Therapy in Patients with Critical Limb Ischemia (BEST-CLI) Trial
title_sort best endovascular versus best surgical therapy in patients with critical limb ischemia (best-cli) trial
publisher Radcliffe Medical Media
publishDate 2020
url https://doaj.org/article/89debc152d0d4e1eb45cd94e7bd8247d
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AT mattkoopman bestendovascularversusbestsurgicaltherapyinpatientswithcriticallimbischemiabestclitrial
AT alikfarber bestendovascularversusbestsurgicaltherapyinpatientswithcriticallimbischemiabestclitrial
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