Comparative analysis of IL-1β blood serum concentration, neutrophil-to-lymphocytes ratio in peripheral blood, and the levels of PD-L1 expression in malignant tissues of the patients with various solid tumors

Comparative analysis of IL-1β blood serum concentration, neutrophil-to-lymphocytes ratio in peripheral blood, and the levels of PD-L1 expression in malignant tissues of the patients with various solid tumors

The action of checkpoint inhibitors is based on activation of T cell antitumor immunity, and, therefore, the search for markers of lymphocyte functional activity before starting the therapy is highly relevant. Determination of the PD-L1 expression in tumor tissues reflects immunosuppressive activity...

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Bibliographic Details
Main Authors: R. V. Orlova, N. V. Zhukova, A. M. Malkova, E. A. Kaledina, A. R. Gubal, V. V. Sharoiko
Format: article
Language:RU
Published: SPb RAACI 2021
Subjects:
il-1β
neutrophil-to-lymphocyte ratio
pd-l1
correlation
solid tumors
immune therapy
Immunologic diseases. Allergy
RC581-607
Online Access:https://doaj.org/article/89e5e681f839483e8ece0ac509e6432f
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https://doaj.org/article/89e5e681f839483e8ece0ac509e6432f

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