TRPM2 contributes to neuroinflammation and cognitive deficits in a cuprizone-induced multiple sclerosis model via NLRP3 inflammasome

Multiple sclerosis (MS) is a disease of the central nervous system (CNS) that is characterized by demyelination, axonal injury and neurological deterioration. Few medications are available for progressive MS, which is associated with neuroinflammation confined to the CNS compartment. Transient recep...

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Autores principales: Yu Shao, Chen Chen, Tao Zhu, Zengxian Sun, Shufen Li, Lifen Gong, Xinyan Dong, Weida Shen, Linghui Zeng, Yicheng Xie, Peifang Jiang
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
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Acceso en línea:https://doaj.org/article/89eb03370a3d4e94bc1d493d08c73f5a
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