Nrf1 promotes heart regeneration and repair by regulating proteostasis and redox balance
Following injury, cells in regenerative tissues can regrow, but how they adapt to injury conditions to regenerate the tissue is unclear. Here the authors identify a stress-responsive and cardioprotective factor Nrf1 that is critical for neonatal heart regeneration.
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Main Authors: | Miao Cui, Ayhan Atmanli, Maria Gabriela Morales, Wei Tan, Kenian Chen, Xue Xiao, Lin Xu, Ning Liu, Rhonda Bassel-Duby, Eric N. Olson |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
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Subjects: | |
Online Access: | https://doaj.org/article/89eb90c4780e4ba9b3c7d007980a5bab |
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