Multi-objective optimization of tumor response to drug release from vasculature-bound nanoparticles

Abstract The pharmacokinetics of nanoparticle-borne drugs targeting tumors depends critically on nanoparticle design. Empirical approaches to evaluate such designs in order to maximize treatment efficacy are time- and cost-intensive. We have recently proposed the use of computational modeling of nan...

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Bibliographic Details
Main Authors: Ibrahim M. Chamseddine, Hermann B. Frieboes, Michael Kokkolaras
Format: article
Language:EN
Published: Nature Portfolio 2020
Subjects:
R
Q
Online Access:https://doaj.org/article/8a0167d8fb7d4229940e465c3c64bf84
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