Histone H3K27M Mutation Overrides Histological Grading in Pediatric Gliomas
Abstract Pediatric high-grade gliomas (HGG) are rare aggressive tumors that present a prognostic and therapeutic challenge. Diffuse midline glioma, H3K27M–mutant is a new entity introduced to HGG in the latest WHO classification. In this study we evaluated the presence of H3K27M mutation in 105 tumo...
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Autores principales: | , , , , , , , , , |
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Formato: | article |
Lenguaje: | EN |
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Nature Portfolio
2020
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Acceso en línea: | https://doaj.org/article/8a04d8c9e4a441e288eb794de5590171 |
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