Histone H3K27M Mutation Overrides Histological Grading in Pediatric Gliomas

Histone H3K27M Mutation Overrides Histological Grading in Pediatric Gliomas

Abstract Pediatric high-grade gliomas (HGG) are rare aggressive tumors that present a prognostic and therapeutic challenge. Diffuse midline glioma, H3K27M–mutant is a new entity introduced to HGG in the latest WHO classification. In this study we evaluated the presence of H3K27M mutation in 105 tumo...

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Autores principales: Amal Mosaab, Moatasem El-Ayadi, Eman N. Khorshed, Nada Amer, Amal Refaat, Mohamed El-Beltagy, Zeinab Hassan, Sameh H. Soror, Mohamed Saad Zaghloul, Shahenda El-Naggar
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/8a04d8c9e4a441e288eb794de5590171
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