Binding of human milk to pathogen receptor DC-SIGN varies with bile salt-stimulated lipase (BSSL) gene polymorphism.
<h4>Objective</h4>Dendritic cells bind an array of antigens and DC-SIGN has been postulated to act as a receptor for mucosal pathogen transmission. Bile salt-stimulated lipase (BSSL) from human milk potently binds DC-SIGN and blocks DC-SIGN mediated trans-infection of CD4(+) T-lymphocyte...
Guardado en:
Autores principales: | Martijn J Stax, Marloes A Naarding, Michael W T Tanck, Susanne Lindquist, Olle Hernell, Robert Lyle, Per Brandtzaeg, Merete Eggesbø, Georgios Pollakis, William A Paxton |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2011
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Materias: | |
Acceso en línea: | https://doaj.org/article/8a173af89c9c443c88795ef61dffd475 |
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