Large-scale viral genome analysis identifies novel clinical associations between hepatitis B virus and chronically infected patients

Abstract Despite the high global prevalence of chronic hepatitis B (CHB) infection, datasets covering the whole hepatitis B viral genome from large patient cohorts are lacking, greatly limiting our understanding of the viral genetic factors involved in this deadly disease. We performed deep sequenci...

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Auteurs principaux: Ondrej Podlaha, Edward Gane, Maurizia Brunetto, Scott Fung, Wan-Long Chuang, Calvin Q. Pan, Zhaoshi Jiang, Yang Liu, Neeru Bhardwaj, Prasenjit Mukherjee, John Flaherty, Anuj Gaggar, Mani Subramanian, Namiki Izumi, Shalimar, Young-Suk Lim, Patrick Marcellin, Maria Buti, Henry L. Y. Chan, Kosh Agarwal
Format: article
Langue:EN
Publié: Nature Portfolio 2019
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Accès en ligne:https://doaj.org/article/8a1e909a6e354d32b320dc74b869d649
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