Enantioselective decarboxylative chlorination of β-ketocarboxylic acids

Due to the synthetic utility of the products, stereoselective halogenation is a powerful method for the synthesis of chiral compounds. Here the authors report an enantioselective decarboxylative chlorination, giving access to a range of α-chloroketones.

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Autores principales: Kazutaka Shibatomi, Kazumasa Kitahara, Nozomi Sasaki, Yohei Kawasaki, Ikuhide Fujisawa, Seiji Iwasa
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/8a1fb464d9784853b979dcc531bb5c93
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