Enantioselective decarboxylative chlorination of β-ketocarboxylic acids

Due to the synthetic utility of the products, stereoselective halogenation is a powerful method for the synthesis of chiral compounds. Here the authors report an enantioselective decarboxylative chlorination, giving access to a range of α-chloroketones.

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Autores principales:	Kazutaka Shibatomi, Kazumasa Kitahara, Nozomi Sasaki, Yohei Kawasaki, Ikuhide Fujisawa, Seiji Iwasa
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/8a1fb464d9784853b979dcc531bb5c93
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spelling	oai:doaj.org-article:8a1fb464d9784853b979dcc531bb5c932021-12-02T17:06:20ZEnantioselective decarboxylative chlorination of β-ketocarboxylic acids10.1038/ncomms156002041-1723https://doaj.org/article/8a1fb464d9784853b979dcc531bb5c932017-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms15600https://doaj.org/toc/2041-1723Due to the synthetic utility of the products, stereoselective halogenation is a powerful method for the synthesis of chiral compounds. Here the authors report an enantioselective decarboxylative chlorination, giving access to a range of α-chloroketones.Kazutaka ShibatomiKazumasa KitaharaNozomi SasakiYohei KawasakiIkuhide FujisawaSeiji IwasaNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-7 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Kazutaka Shibatomi Kazumasa Kitahara Nozomi Sasaki Yohei Kawasaki Ikuhide Fujisawa Seiji Iwasa Enantioselective decarboxylative chlorination of β-ketocarboxylic acids
description	Due to the synthetic utility of the products, stereoselective halogenation is a powerful method for the synthesis of chiral compounds. Here the authors report an enantioselective decarboxylative chlorination, giving access to a range of α-chloroketones.
format	article
author	Kazutaka Shibatomi Kazumasa Kitahara Nozomi Sasaki Yohei Kawasaki Ikuhide Fujisawa Seiji Iwasa
author_facet	Kazutaka Shibatomi Kazumasa Kitahara Nozomi Sasaki Yohei Kawasaki Ikuhide Fujisawa Seiji Iwasa
author_sort	Kazutaka Shibatomi
title	Enantioselective decarboxylative chlorination of β-ketocarboxylic acids
title_short	Enantioselective decarboxylative chlorination of β-ketocarboxylic acids
title_full	Enantioselective decarboxylative chlorination of β-ketocarboxylic acids
title_fullStr	Enantioselective decarboxylative chlorination of β-ketocarboxylic acids
title_full_unstemmed	Enantioselective decarboxylative chlorination of β-ketocarboxylic acids
title_sort	enantioselective decarboxylative chlorination of β-ketocarboxylic acids
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/8a1fb464d9784853b979dcc531bb5c93
work_keys_str_mv	AT kazutakashibatomi enantioselectivedecarboxylativechlorinationofbketocarboxylicacids AT kazumasakitahara enantioselectivedecarboxylativechlorinationofbketocarboxylicacids AT nozomisasaki enantioselectivedecarboxylativechlorinationofbketocarboxylicacids AT yoheikawasaki enantioselectivedecarboxylativechlorinationofbketocarboxylicacids AT ikuhidefujisawa enantioselectivedecarboxylativechlorinationofbketocarboxylicacids AT seijiiwasa enantioselectivedecarboxylativechlorinationofbketocarboxylicacids
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Enantioselective decarboxylative chlorination of β-ketocarboxylic acids

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