Heme uptake by Leishmania amazonensis is mediated by the transmembrane protein LHR1.

Trypanosomatid protozoan parasites lack a functional heme biosynthetic pathway, so must acquire heme from the environment to survive. However, the molecular pathway responsible for heme acquisition by these organisms is unknown. Here we show that L. amazonensis LHR1, a homolog of the C. elegans plas...

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Autores principales: Chau Huynh, Xiaojing Yuan, Danilo C Miguel, Rebecca L Renberg, Olga Protchenko, Caroline C Philpott, Iqbal Hamza, Norma W Andrews
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/8a247c87896f4dc798eb7cceb901a990
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