A Novel, Drug Resistance-Independent, Fluorescence-Based Approach To Measure Mutation Rates in Microbial Pathogens

ABSTRACT All evolutionary processes are underpinned by a cellular capacity to mutate DNA. To identify factors affecting mutagenesis, it is necessary to compare mutation rates between different strains and conditions. Drug resistance-based mutation reporters are used extensively to measure mutation r...

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Autores principales: Erika Shor, Jessica Schuyler, David S. Perlin
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2019
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GFP
Acceso en línea:https://doaj.org/article/8a2ade67478c48e6ae6767b3d22fe616
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