Transcriptional effects of copy number alterations in a large set of human cancers

Transcriptional effects of copy number alterations in a large set of human cancers

Copy number alterations (CNAs) can drive tumor progression in cancer by altering gene expression levels, but transcriptional adaption can skew CNA impact. Here, the authors present transcriptional adaptation to CNA (TACNA) profiling; a tool to extract the transcriptional effect of CNAs from expressi...

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Autores principales: Arkajyoti Bhattacharya, Rico D. Bense, Carlos G. Urzúa-Traslaviña, Elisabeth G. E. de Vries, Marcel A. T. M. van Vugt, Rudolf S. N. Fehrmann
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Science
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Acceso en línea:https://doaj.org/article/8a30eeb79fbb4839b329f70a9a9b4653
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