Evolutionary analysis of human immunodeficiency virus type 1 therapies based on conditionally replicating vectors.

Efforts to reduce the viral load of human immunodeficiency virus type 1 (HIV-1) during long-term treatment are challenged by the evolution of anti-viral resistance mutants. Recent studies have shown that gene therapy approaches based on conditionally replicating vectors (CRVs) could have many advant...

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Autores principales: Ruian Ke, James O Lloyd-Smith
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/8a34b565a0fb4c28b7d77b569d94daaa
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