Evolutionary analysis of human immunodeficiency virus type 1 therapies based on conditionally replicating vectors.
Efforts to reduce the viral load of human immunodeficiency virus type 1 (HIV-1) during long-term treatment are challenged by the evolution of anti-viral resistance mutants. Recent studies have shown that gene therapy approaches based on conditionally replicating vectors (CRVs) could have many advant...
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Main Authors: | Ruian Ke, James O Lloyd-Smith |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2012
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Online Access: | https://doaj.org/article/8a34b565a0fb4c28b7d77b569d94daaa |
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