Hydrogen bonds in polycation improve the gene delivery efficiency in the serum-containing environment
Cationic polymers with high charge density could effectively condense the DNA and achieve gene transfection; however, it often brings non-negligible cytotoxicity. Notably, the high charge density gene vector fails in the serum environment, limiting further application in vivo. In this paper, an effi...
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Autores principales: | , , , |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/8a3a76071f8f45f3b4780d0372349781 |
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