Functional characterisation of the WW minimal domain for delivering therapeutic proteins by adenovirus dodecahedron.

Protein transduction offers a great therapeutic potential by efficient delivery of biologically active cargo into cells. The Adenovirus Dd (Dodecahedron) has recently been shown to deliver proteins fused to the tandem WW(2-3-4) structural domains from the E3 ubiquitin ligase Nedd4. In this study, we...

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Autores principales: Ana Villegas-Méndez, Pascal Fender, Marina I Garin, Romy Rothe, Lavinia Liguori, Bruno Marques, Jean-Luc Lenormand
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/8a441a9e95964defaeaa1895be2f9368
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