Epigenetic landscapes explain partially reprogrammed cells and identify key reprogramming genes.
A common metaphor for describing development is a rugged "epigenetic landscape" where cell fates are represented as attracting valleys resulting from a complex regulatory network. Here, we introduce a framework for explicitly constructing epigenetic landscapes that combines genomic data wi...
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Main Authors: | , , , |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2014
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Subjects: | |
Online Access: | https://doaj.org/article/8a4fd51465244b7eabf47a56bd2bd5d2 |
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